Modular, automated flow synthesis of spirocyclic tetrahydronaphthyridines from primary alkylamines
Posted on: March 4, 2026
The Cresswell Group, led by Dr Alexander J. Cresswell at the University of Bath (UK), have demonstrated the synthesis of a number of spirocyclic tetrahydonaphthyridines (THNs) expanding the chemical space of these important scaffolds for drug discovery.